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AstraZeneca: Trust me (on guidance), I’m a doctor

AstraZeneca may not be the UK Index ’s heaviest faller this morning (that prize goes to JMAT). However, by virtue of its heavyweight status (2.9% weighting) it is inflicting the most damage, taking almost 6pts off the index. This comes after Q1 results missed consensus expectations; revenues by a shade, profits by rather more, as product sales remained under pressure and costs rose.

Revenues -4% to $5.18bn (-9% at constant FX), despite product Sales +3% to $5bn (-2% at constant FX), was just below $5.2bn consensus. However, it highlights; 1) a flattering 5% FX tailwind, and; 2) a significant plunge (-66%) in “externalisation revenues” which include proceeds from licensing & partnership deals (royalties, milestones) booked as sales.

The generic erosion of sales of its blockbuster ($1bn sales per year) statin Crestor was also greater than expected (-38%) hurting the CVRM franchise (-8%), Respiratory sales were flat, although this was offset to some extent by strong Oncology (+39%), sales in China (+31%) and Emerging Markets +13% we well as new treatment launches across multiple therapies.

The real disappointment, however, comes from a 9% miss for Core Earnings ($0.48 per share versus $0.57 expectations), down circa 50% on Q1 last year. FX moves also increased most of the cost base (COGS, Distribution, SG&A), fuelled by new launches, but this easily overpowered efficiency savings in R&D to hammer margins down through the P&L.

Even if management says trading is in-line, and left full year sales and profits guidance unchanged, investors are sceptical enough about whether sales growth can recover over the course of the year (“H2 weighted”) to send the shares 2-3% lower. There’s a lot riding on recent launches to get product sales back to growth. Q2 and Q3 could thus be make or break.

Mike van Dulken, Head of Research, 18 May 2018

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This research is produced by Accendo Markets Limited. Research produced and disseminated by Accendo Markets is classified as non-independent research, and is therefore a marketing communication. This investment research has not been prepared in accordance with legal requirements designed to promote its independence and it is not subject to the prohibition on dealing ahead of the dissemination of investment research. This research does not constitute a personal recommendation or offer to enter into a transaction or an investment, and is produced and distributed for information purposes only.

Accendo Markets considers opinions and information contained within the research to be valid when published, and gives no warranty as to the investments referred to in this material. The income from the investments referred to may go down as well as up, and investors may realise losses on investments. The past performance of a particular investment is not necessarily a guide to its future performance. Prepared by Michael van Dulken, Head of Research

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